These doors had been closed and could not be opened when you may have been here previously. But they are now open and invite the party to the portal at 4.
Bence Duncan and a few other Coalition soldiers will be at this door. He'll advise you that a strange aura is behind the door, and that Caelar is waiting behind it.
You can postpone going through the door with the choice to speak again to Bence Duncan and go through the door later. But once you go through the door to confront Caelar at 4, there's no going back. Bence Duncan will keep the door locked behind you, and the only way out is to somehow close the portal that forms at 4.
Coming here is the moment Hephernaan betrays Caelar by including everyone, the party, the Crusaders, and Caelar herself, in his spell of paralysis. He also grabs the opportunity to use the Child of Bhaal's blood to open a portal to the Nine Hells on the floor.
He himself goes through the portal to prepare the Devils of the Nine Hells for their invasion of the Prime Material Plane. Caelar takes her Crusaders with her through the portal to pursue him. The Portal itself is now available to enter Avernus and start Chapter 12.
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